Randox pledges support for PSNI in the fight against fentanyl

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Randox pledges support for PSNI in the fight against fentanyl

Global drug tests provider Randox Toxicology has today pledged its support for the PSNI in the fight against fentanyl, a strong painkiller which has been found for sale on the black market in Northern Ireland for the first time.

Fentanyl, which is an opioid pain medication currently classed as a controlled Class A drug under the Misuse of Drugs Act 1971, has been found in heroin which was seized by the PSNI, and has been linked to two deaths in Northern Ireland this year.

It is currently used to safely treat patients with severe pain, as it can be 50 to 100 times more potent than morphine. According to the National Crime Agency and Office for National Statistics however, 60 deaths in the UK in the past eight months have been attributed to misuse of fentanyl, which received international attention when the singer Prince was found to have died from a fentanyl overdose.

Dr. Peter FitzGerald, Founder and Managing Director of Randox Laboratories, commented;

“It is extremely worrying to hear that the PSNI have confirmed fentanyl has reached the black market in Northern Ireland.  The illegal sale of the painkiller has long been an issue in the USA, with the country having at least two million opioid addicts, but until now has not been used illegally in NI.

“Fentanyl’s status as a painkiller is potentially why it is so commonly abused, as those using prescription painkillers may turn to illicit substances, such as fentanyl, when their prescriptions run out.  With as little as 2mg able to cause an overdose, fentanyl is easily hidden and transported in small packages through the post, so poses a major danger to society.  The drug has high abuse potential and is being used more and more by drug dealers who can sell fentanyl at a cheaper price than heroin.”

Randox Toxicology, a specialist division of FitzGerald’s Antrim-headquartered Randox Laboratories, has today issued a statement to pledge its commitment to removing the danger of fentanyl from Northern Ireland.  The company’s significant investment in the research and development of new tests for drug detection has cemented its status at the forefront of the drugs screening industry.  Randox Toxicology, which developed its first fentanyl test in 2007, has the world’s only tests for the designer opiates U-47700, MT-45 and AH-7921.

Dr. Joanne Darragh, Head of Research and Development at Randox Toxicology, commented;

“In the endless pursuit of creating innovative tests for new drugs which emerge weekly on to the market, our expertise at Randox Toxicology sets us apart from the rest of the industry.  Not only have we been first to market with a number of opioid tests, but we have also developed our patented Biochip Array Technology, which enables us to simultaneously screen for both fentanyl and heroin, one of which may have been laced with the other.

“Today we pledge the support of our expertise, based on a decade’s worth of experience in developing fentanyl tests, to the PSNI in their efforts to remove the fentanyl threat from Northern Ireland. This is a problem that we must tackle together and we are confident that by highlighting this growing epidemic, we can educate communities on the devastating effects the misuse of fentanyl can have.”

For further information about Randox Toxicology’s fentanyl screrening please contact Randox PR on 028 9445 1016 or email RandoxPR@randox.com


Evidence Series Immunoanalysers

 

Powered by Biochip Array Technology

In 2002, Randox invented a world first, Biochip Array Technology (BAT), instantly changing the landscape of diagnostic testing forever. BAT is a multi-analyte platform which provides an unrivaled increase in patient information per sample. Instead of a patient sample needing to be subdivided for each test result, or in some cases re-collected, Biochip Array Technology offers a diagnostic patient profile with each patient sample. So now the patient’s needs become the focus, as BAT delivers the multiple results needed for improved diagnosis.

With over £250 million invested into Biochip Array Technology research and development, Randox have launched a range of Biochip Array Technology immunoanalysers – The Evidence Series. This includes the Evidence, the Evidence Investigator and the Evidence MultiSTAT. Each analyser is developed with boundary pushing engineering, designed to make financial, labour and time savings for the end user. Utilising this technology, the Evidence series guarantees cost-effective, highly accurate and flexible testing solutions.

Click on the immunoanalysers below for more information

Evidence Investigator

Evidence MultiSTAT

Evidence

Why choose the Evidence Series?

  • Biochip Array Technology has a proven high standard of precise test results with CVs <10%
  • Multiplex testing reduces the amount of time and labour spent on individual tests and associated laboratory costs
  • Simultaneous testing represents greater value for money as fewer patient samples are able to deliver more in-depth analysis
  • Testing for multiple markers simultaneously increases the amount of patient information rapidly available to the clinician, allowing for more informed diagnosis
  • Randox has the world's most innovative test development program, ensuring that with Biochip Array Technology you are able to offer improved options from your laboratory
  • Multiple sample types can be used on one immunoanalyser including serum, plasma, whole blood, urine and oral fluid
  • Vast Biochip Array Technology test menu allows clinicians to detect routine and novel markers for advanced analysis
  • Through utilising a smaller sample volume, more assays can be run without needing further collections

Biochip Array Technology Test Menu

Adhesion Molecules
E-Selectin P-Selectin L-Selectin
Intercellular Adhesion Molecule-I – ICAM-I Vascular Cell Adhesion Molecule-I –VCAM-I
Alzheimer’s
Apolipoprotein E4 –ApoE4 Pan Apolipoprotein E – Apo E
Anaemia
Ferritin Folate Vitamin B12
Bone Disease
Vitamin D
Cancer
Carcinoembryonic Antigen – CEA Free Prostate Specific Antigen − FPSA Total Prostate Specific Antigen − TPSA
Cardiac
Cardiac Troponin I – cTnl Creatine Kinase MB – CKMB Heart Fatty Acid Binding Protein – H-FABP Myoglobin
Cerebral
Brain-Derived Neurotrophic Factor − BDNF Neuron Specific Enolase − NSE
Cytokines
Epidermal Growth Factor − EGF Granulocyte Macrophage Colony Stimulating Factor Interferon-γ − IFN-γ Interleukin-1 alpha − IL-1α
Interleukin-1 beta − IL-1β Interleukin-2 − IL-2 Interleukin-3 − IL-3 Interleukin-4 − IL-4
Interleukin-5 − IL 5 Interleukin-6 − IL-6 Interleukin-7 − IL-7 Interleukin-8 − IL-8
Interleukin-4 − IL-4 Interleukin-5 − IL 5 Interleukin-6 − IL-6 Interleukin-7 − IL-7
Interleukin-8 − IL-8 Interleukin-10 − IL-10 Interleukin-12p70 − IL-12p70 Interleukin-13 − IL-13
Interleukin-15 − IL 15 Interleukin-23 − IL-23 Macrophage Infl ammatory Protein-1α − MIP-1α Matrix Metalloproteinase 9 − MMP 9
Monocyte Chemotactic Protein-1 − MCP-1 Soluble IL-2 Receptor Alpha − sIL-2Rα Soluble IL-6 Receptor − sIL-6R Soluble Tumour Necrosis Factor Receptor 1 − sTNFR1
Soluble Tumour Necrosis Factor Receptor 2 − sTNFR2 Tumour Necrosis Factor-α − TNF-α Vascular Endothelial Growth Factor − VEGF
Diabetes
Insulin
Endocrine
Cortisol Dehydroepiandrosterone-Sulphate- DHEAS
Fertility / Pregnancy
Estradiol Follicle Stimulating Hormone − FSH Luteinizing Hormone − LH Progesterone
Prolactin Sex Hormone Binding Globulin − SHBG Testosterone
Fibrinolysis
D-Dimer
Gastro
Gastrin 17 – GI7 Helicobacter pylori – H. pylori Pepsinogen I – PGI Pepsinogen II – PGII
Metabolic
Adiponectin Ferritin Insulin Leptin
Plasminogen Activator Inhibitor − PAI-1 Resistin
Renal
Adiponectin Complement C3a des Arginine – C3a des Arg CRP (C-Reactive Protein) Cystatin C
D-Dimer Epidermal Growth Factor − EGF Fatty Acid Binding Protein-1 − FABP1 Interleukin-8 − IL-8
Macrophage Infl ammatory Protein-1α − MIP-1α Neutrophil Gelatinase – Associated Lipocalin – NGAL Soluble Tumour Necrosis Factor Receptor 1 − sTNFR1 Soluble Tumour Necrosis Factor Receptor 2 − sTNFR2
Stroke
Brain-Derived Neurotrophic Factor − BDNF D-Dimer Glial Fibrillary Acidic Protein − GFAP Glutathione S – Transferase Pi – GSTPi
Heart Fatty Acid Binding Protein – H-FABP Interleukin-6 − IL-6 Nucleoside Diphosphate Kinase – NDKA Neuron Specifi c Enolase − NSE
Parkinson Protein 7 − PARK-7 Soluble Tumour Necrosis Factor Receptor 1 − sTNFR1
Thyroid
Anti-Thyroglobulin − Anti-Tg Anti-Thyroid Peroxidase − Anti-TPO Free Tri-iodothyronine − FT3 Free Thyroxine − FT4
Thyroid Stimulating Hormone − TSH Thyroxine Binding Globulin − TBG Total Tri-iodothyronine − TT3 Total Thyroxine − TT4
Toxicology
Amphetamine Barbiturates Benzodiazepines I Benzodiazepines II
Buprenorphine Cannabinoids – THC Cocaine Metabolite Dextromethorphan
Fentanyl Ketamine Meprobamate Methadone
Opiate Oxycodone I Oxycodone II Phencyclidine – PCP
Tramadol Tricyclic Antidepressants Zolpidem
Molecular
20 SNPs Adenovirus A/B/C/D/E APOB – 1 mutation Bordetella pertussis
BRAF – 1 mutation Chlamydia trachomatis – (CT) Chlamydophila pneumoniae Coronavirus 229E/NL63
Coronavirus OC43/HKU1 Enterovirus A/B/C Haemophilus ducreyi – (HD) Haemophilus influenzae
Herpes simplex Virus 1– (HSV-1) Herpes simplex Virus 2 – (HSV-2) Human Bocavirus 1/2/3 Human Metapneumovirus – hMPV
Influenza A/B KRAS – 16 mutations LDLR – 38 mutations Legionella pneumophila
Moraxella catarrhalis Mycoplasma genitalium – (MG) Mycoplasma hominis – (MH) Mycoplasma pneumoniae
Neisseria gonorrhoea – (NG) Parainfluenza Virus 1/2/3/4 PCSK9 – 1 mutation PIK3CA – 3 mutations
Respiratory Syncytial Virus a – RSVa Respiratory Syncytial Virus b – RSVb Rhinovirus A/B Streptococcus pneumoniae
Treponema pallidum – (TP) Trichomonas vaginalis – (TV) Ureaplasma urealyticum – (UU)
Veterinary Residues / Food Diagnostics
17β-Clostebol 5-hydroxy Flunixin Aflatoxin B1 Aflatoxin G1/G2
Aflatoxin M1 AHD Amikacin/Kanamycin Amino Benzimidazoles
Amoxicillin AMOZ Amphenicols Ampicillin
AOZ Apramycin Avermectins Bacitracin
Baquiloprim Benzimidazoles Beta-agonists Beta-Lactams
Boldenone Cefapirin Cefoperazone Cefquinome
Ceftiofur Cefuroxime Cephalexin Cephalonium
Chloramphenicol Chlormadinone Clopidol Cloxacillin
Corticosteroids Dapsone Decoquinate Deoxynivalenol
Dexamethasone Diacetoxyscirpenol Diclazuril Dicloxacillin
Dihydrostreptomycin Ergot Alkaloids Erythromycin Ethinylestradiol
Fumonisins Gentamicin Gestagens Halofugine
Hygromycin B Imidocarb Kanamycin Lasalocid
Levamisole Lincomycin Lincosamides MaduramicinG
Melamine Meloxicam Metamizole Methyltestosterone
Monensin Moxidectin (MXD) Nandrolone Neomycin/Paromomycin
Nicarbazin Nitroimidazoles Nitroxynil Novobiocin
Ochratoxin A Oxacillin Paxilline Penicillin G
Penicillin V Phenylbutazone Pirlimycin Polymixins
Quinolones Ractopamine Rifaximin Robenidine
Salinomycin SEM Spectinomycin Spiramycin
Spiramycin/Josamycin Stanozolol Stilbenes Streptomycin
Sulfaguanidine Sulfamethazine Sulphachlorpyridazine Sulphadiazine
Sulphadimethoxine Sulphadoxine Sulphamerazine Sulphamethazine
Sulphamethizole Sulphamethoxazole Sulphamethoxypyridazine Sulphapyridine
Sulphaquinoxaline Sulphathiazole Sulphisoxazole Sulphonamides
T2 toxin Tetracyclines Thiabendazole Thiamphenicol
Tobramycin Tolfenamic Acid Toltrazuril Trenbolone
Triclabendazole Trimethoprim Tylosin Tylosin B/Tilmicosin
Virginiamycin Virginiamycin M1 Zearalenone Zeranol

We Are Randox | Omagh Speed Networking promotes careers in STEM

We’re sure you’ve heard of “Speed Dating”, but what about “Speed Networking”? Randox’s R&D Scientist, Dr. Dwaine Vance tried it out to spread the word about Randox Careers in STEM!

Dr Dwaine Vance visited Omagh High School to represent Randox Careers. He sat down with us, and we discussed the importance of the event. Dr. Vance told us:

On Wednesday the 15th June I represented Randox Careers at a ‘speed networking’ event at Omagh High School. This involved groups of students moving from one employer stand to the next for a 5 minute ‘mini network’. There was two sessions during the morning involving GCSE level pupils. The aim of the ‘speed networking’ event was to provide pupils with opportunities to meet local Northern Irish companies within the Science, Technology, Engineering and Mathematics (STEM) sectors, of which Randox Laboratories play a pivotal role.

We, at Randox, want to inspire students to think about their own career plans and to allow them to gather information about the local job market. By doing this, we’re also giving them the opportunity to be aware of the jobs that are available and the importance of STEM related subjects,  as well as letting them see how employers value their other curriculum subjects and their personal skills and attributes.   My objective as a employee of Randox was to showcase a range of careers for all abilities within the company with a focus on STEM careers e.g. science and engineering.

The importance of spreading awareness of the opportunities in science and engineering from a young age is imperative, as many students are unaware of the vast range of differentiation in different careerpaths, stemming from one subject or degree class. Dr. Dwaine Vance went on to discuss the events of the networking conference:

As part of each ‘mini network’ I provided students with a brief overview of Randox. Students were given the opportunity to watch videos depicting our expertise and to ask questions about how their interests could be incorporated within Randox. The training department at Randox provided me with pop-up stands, recruitment pathway brochures, merchandise e.g. pens, stopwatches, mug coasters and even Biochip Array Technology key rings!

Overall the students gained a good knowledge of Randox, they were particularly keen to learn about the local and global opportunities available at Randox. In addition, students were keen to know more about the veterinary aspect of Randox. It was comforting to discover that the majority of pupils had previous knowledge of the Randox brand from the press (as we have recently experienced a great boost in brand visibility through Grand national sponsorship), Randox health (television adverts) and Confidante (local radio stations).

The pupils at Omagh High School were keen to ask me about my role within the company and what my day to day roles and responsibilities are. I was happy to provide students with my research and development activities and they were interested to hear that I was involved in the development of a genetic test that aims to predict your future risk of heart disease by investigating your own DNA.

At Randox I am part of a small team of experienced research scientists that are developing a genetic risk prediction test for heart disease and myocardial infarction. This test aims to simultaneously genotype 20 genetics variants that have been previously associated with increased risk of heart disease. This Randox molecular test is in collaboration with leading University academics and will help reduce the burden of heart disease throughout the world by providing an accurate risk assessment of disease so personalised treatment can be provided to those who require it most. To quote Randox Health, “Prevention is better than cure”.

From everyone at the Randox Careers team and from Dr. Dwaine Vance, we’d like to thank Omagh High School for inviting us to attend this incredibly beneficial Speed Networking event, where we feel we have truly impacted the young minds of tomorrow. We look forward to the future of diagnostics, with you!

Dr Dwaine Vance at Omagh High School to promote Careers in STEM
Dr Dwaine Vance, pictured with Mrs. Paula Burns, teacher and Head of Careers at Omagh High School at STEM event

Drugs of Abuse Array V Quality Control

Therapeutic Drug Quality Control

Assayed quality control for use in monitoring the accuracy and precision of 10 drugs of abuse on Randox Biochip systems. Two levels of control are provided covering the cut-off range.

Features & Benefits

  • Lyophilised for enhanced stability
  • Stable to expiry date at 2oC – 8oC
  • Reconstituted stability of 7 days at 2oC – 8oC
DescriptionSizeAnalytesCat No
Drugs of Abuse Array V (Urine) Control4 x 2 x 1 ml10EV3814
Drugs of Abuse Array V (Urine) Calibrator Series9 x 1 ml10EV3815
Drugs of Abuse Array V (Whole Blood) Control4 x 2 x 1 ml10EV3848
Drugs of Abuse Array V (Whole Blood) Calibrator Series9 x 1 ml10EV3847

Analytes

  • Bath Salts 1 (Methcathinone and Mephedrone)
  • Bath Salts 2 (MDPV)
  • Benzylpiperazines
  • Mescaline
  • Phenylpiperazines
  • Salvinorin
  • Synthetic Cannabinoids 1
  • Synthetic Cannabinoids 2
  • Synthetic Cannabinoids 3
  • Synthetic Cannabinoids 4

Drugs of Abuse Array IV Quality Control

Therapeutic Drug Quality Control

Assayed quality control for use in monitoring the accuracy and precision of 14 drugs of abuse on Randox Biochip systems. Two levels of control are provided covering the cut-off range.

Features & Benefits

  • Lyophilised for enhanced stability
  • Stable to expiry date at 2oC – 8oC
  • Reconstituted stability of 7 days at 2oC – 8oC
DescriptionSizeAnalytesCat No
Drugs of Abuse Array IV (Urine) Control4 x 2 x 1ml14EV3835
Drugs of Abuse Array IV (Whole Blood) Control4 x 2 x 1ml14EV3809

Analytes

  • Acetaminophen
  • Dextromethorphan
  • Escitalopram
  • Fluoxetine
  • Haloperidol
  • Ibuprofen
  • Methylphenidate
  • Salicylate
  • Salicyluric Acid
  • Sertraline
  • Tramadol
  • Trazodone
  • Tricyclic Antidepressants
  • Creatinine

Drugs of Abuse Array III Quality Control

Therapeutic Drug Quality Control

Assayed quality control for use in monitoring the accuracy and precision of 11 drugs of abuse on Randox Biochip systems. Two levels of control are provided covering the cut-off range.

Features & Benefits

  • Lyophilised for enhanced stability
  • Stable to expiry date at 2oC – 8oC
  • Reconstituted stability of 7 days at 2oC – 8oC
DescriptionSizeAnalytesCat No
Drugs of Abuse Array III (Urine) Control4 x 2 x 1 ml11EV3830
Drugs of Abuse Array III (Whole Blood) Control4 x 2 x 1 ml11EV3794

Analytes

  • Chloral Hydrate Metabolite
  • Ethyl Glucuronide
  • Fentanyl
  • Ketamine Metabolite
  • Meperidine
  • Meprobamate
  • Zaleplon
  • Zolpidem
  • Zopiclone
  • 7-amino Flunitrazepam
  • Creatinine

Drugs of Abuse Array II Quality Control

Therapeutic Drug Quality Control

A comprehensive quality control designed for use in the routine monitoring of accuracy and precision on Randox Biochip systems. Target values are provided for 11 drugs of abuse.

Features & Benefits

  • Lyophilised for enhanced stability
  • Stable to expiry at 2oC – 8oC
  • Urine- Reconstituted stability of 7 days at 2oC – 8oC or 28 days at -20oC
  • Whole Blood – Reconstituted stability of 7 days at 2oC – 8oC or 28 days at -20oC
DescriptionSizeAnalytesCat No
Drugs Of Abuse Array II (Urine) Controls2 x 4 x 1 ml11EV3657
Drugs Of Abuse Array II (Whole Blood) Controls2 x 4 x 1 ml11EV3682

Analytes

  • 3,4 Methylenedioxymethamphetamine (MDMA)
  • Ketamine
  • Lysergic Acid Diethylamide (LSD)
  • Methaqualone
  • Buprenorphine
  • Fentanyl
  • Generic Opioids
  • Oxycodone I
  • Oxycodone II
  • Propoxyphene
  • Creatinine

Drugs of Abuse Array I Plus Quality Control

Therapeutic Drug Quality Control

A comprehensive quality control designed for use in the routine monitoring of 14 drugs of abuse on Randox Biochip systems. Two levels of control are provided covering the cut-off range.

Features & Benefits

  • Lyophilised for enhanced stability
  • Stable to expiry date at 2oC – 8oC
  • Urine- Reconstituted stability of 14 days at 2oC – 8oC
  • Whole Blood – Reconstituted stability of 7 days at 2oC – 8oC or 14 days at -20oC
DescriptionSizeAnalytesCat No
Drugs of Abuse Array 1 Plus (Urine) Controls2 x 4 x 1 ml14EV3745
Drugs of Abuse Array 1 Plus (Whole Blood) Controls2 x 4 x 1 ml14EV3750

Analytes

  • Amphetamine
  • Barbiturates
  • Benzodiazepine 1
  • Benzodiazepine 2
  • Buprenorphine
  • Cannabinoids
  • Cocaine Metabolite
  • MDMA
  • Methadone
  • Methamphetamine
  • Opiates
  • Phencyclidine
  • Tricyclic Antidepressants
  • Creatinine (only available in Urine – EV3745)

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