Triglycerides
Reagent | Triglycerides
Key Benefits
Excellent stability
Working reagents stable for 21 days at 2-8⁰C or 3 days at 15-25 °C
Applications available
For a wide variety of clinical chemistry analysers including the RX series
Strong correlation
The Triglycerides assay showed a correlation coefficient of 0.9965 against another commercially available method
Randox Triglycerides (GPO-PAP)
- GPO-PAP method
- Liquid and lyophilised reagents available
- Working reagents stable for 21 days at +2 to +8⁰C or 3 days at +15 to +25 ⁰C
- Applications available
| Cat No | Size | ||||
|---|---|---|---|---|---|
| TR210 | 6 x 15ml (S) | Enquire | Kit Insert Request | MSDS | Buy Online |
| TR1697 | 4 x 100ml (S) | Enquire | Kit Insert Request | MSDS | Buy Online |
| TR3823 | 6 x 51ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| TR8067 | 4 x 58ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| TR9780 | 4 x 58ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| TR8332 | 4 x 20ml (L) | Enquire | Kit Insert Request | MSDS | Buy Online |
| TR8147 | 8 x 20ml (L) | Enquire | Kit Insert Request | MSDS | Buy Online |
| (L) Indicates liquid option (S) Indicates standard included in kit |
|||||
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is Triglycerides assay used for?
Triglyceride measurements are used in the diagnosis and treatment of diseases involving lipid metabolism and various endocrine disorders e.g. diabetes mellitus, nephrosis and liver obstruction.
High levels of triglycerides in the blood are associated with an increased risk of developing cardiovascular disease (CVD). Certain factors can contribute to high triglyceride levels, including lack of exercise, being overweight, smoking cigarettes, consuming excess alcohol, and medical conditions such as diabetes and kidney disease.
Related Products
Standard included in TR210, TR212, TR213, TR1697
Total Cholesterol
Reagent | Total Cholesterol
Key Benefits
Exceptional correlation with standard methods
A correlation coefficient of r=0.99 was obtained with a competitor method
Excellent stability
Stable to expiry when stored at 2-8°C
Liquid ready-to-use
The Randox Cholesterol Total reagent is available in a liquid ready to use format for convenience and ease of use.
Other Features
- Liquid ready-to-use reagents
- Correlation coefficient of r=0.99 with competitor method
- Stable to expiry when stored at 2-8°C
| Cat No | Size | ||||
|---|---|---|---|---|---|
| CH200 | 6 x 30ml (S) | Enquire | Kit Insert Request | MSDS | Buy Online |
| CH3810 | 9 x 51ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| CH8019 | 4 x 68ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| CH8310 | 4 x 20ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| (S) Indicates standard included in kit | |||||
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is Total Cholesterol assay used for?
Cholesterol measurements are used in the diagnosis and treatments of lipid lipoprotein metabolism disorders. Lipids play an important role in the body; they serve as hormones or hormone precursors, aid in digestion, provide energy, storage and metabolic fuels, act as functional and structural components in biomembranes and form insulation to allow nerve conduction and prevent heat loss.
In clinical chemistry, over the last decade however, lipids have become associated with lipoprotein metabolism and atherosclerosis.
A patient will be offered a blood cholesterol level test if they:
- have been diagnosed with coronary heart disease, stroke or mini-stroke
- are over 40
- have a family history of early cardiovascular disease
- have a close family member who has an inherited cholesterol-related condition
- are overweight or obese
- have high blood pressure or diabetes
- Have another medical condition such as a kidney condition, an underactive thyroid gland or pancreatitis
- Sajjadi, S.E., et al. Antihyper lipidemic effect of hydroalcoholic extract, and phenolic fraction from Dracocephalum kotschyi Boiss. Pharmaceutica Acta Helvetiae 1998, 73(3): 167-170
- Wallace, J.M.W., et al. Boron supplementation and activated factor VII in healthy men. EJCN 2002, 56(11): 1102-1107
- Joshi, S., et al. Fish oil supplementation of rats during pregnancy reduces adult disease in their offspring. J. Nutr., 2003, 133: 3170-3174
- Ahmed, H.H. and Manna, F. Curcumin as an effective protective agent against ethinylestradiol-induced hepatocellular cholestasis. EGYPT. J. Med. Lab. Sci. 2004, 13(2)
- Ghorbanihaghjo, A., et al. Effect of nandrolone decanoate on serum lipoprotein (a) and its isoforms in hemodialysis patients. Lipids Health Dis. 2004, 3: 16
- Panagia, M., et al. PPAR-α activation required for decreased glucose uptake and increased susceptibility to injury during ischemia. Am. J. Physiol. Heart Circ. Physiol. 2005, 288: H2677-H2683
- Chen, C-W and Cheng, H-H. A rice bran oil diet increases LDL-receptor and HMG-CoA reductase mRNA expressions and insulin sensitivity in rats with streptozotocin/nicotinamide-induced type 2 diabetes. J. Nutr. 2006, 136: 1472-1476
- Macut, G., et al. Oxidised low-density lipoprotein concentration-early marker of an altered lipid metabolism in young women with PCOS. Eur. J. Endocrinol. 2006, 155: 131-136
- Moreira Lima, L., et al. Níveis Plasmàticos Elevados de Lipoproteína(a) Correlacionados com a Gravidade da Doenca Arterial Coronariana em Pacientes Submetidos à Angiografia (Increased Serum Levels of Lipoprotein(a) Correlated with the Severity of Coronary Artery Disease in Patients Submitted to Angiography. Arquivos Brasileiros de Cardiologia. 2006, 87(3): 260-266
- Oyetayo, F.L. Responses of plasma lipids to edible mushroom diets in albino rats. Afr. J. Biotechnol. 2006, 5(13): 1263-1266
- James, A.P., et al. Prior exercise does not affect chylomicron particle number following a mixed meal of moderate fat content. Lipids Health Dis. 2007, 6: 8
- Shen, L., et al. Hypothalamic apolipoprotein A-IV is regulated by leptin. Endocrinology. 2007, 148(6): 2681-2689
- Lawal, H.A., et al. Hypoglycaemic and hypolipidaemic effects of aqueous leaf extract of Murraya koenigii in normal and alloxan-diabetic rats. Nigerian Journal of Physiological Sciences. 2008, 23(1-2): 37-40
- Mineo, D., et al. Effects of lung volume reduction surgery for emphysema on glycolipidic hormones. Chest. 2008, 134(1): 30-37
- Zaragozá, M.C., et al. Toxicity and antioxidant activity in vitro and in vivo of two Fecus vesiculosus extracts. J. Agric. Food. Chem. 2008, 56: 7773-7780
- Bajaj, S., et al. A case-control study on insulin resistance, metabolic co-variates and prediction score in non-alcoholic fatty liver disease. Indian J. Med. Res. 2009, 129: 285-292
- Chou T-W., et al. A Rice bran oil diet improves lipid abnormalities and suppress hyperinsulinemic responses in rats with streptozotocin/nicotinamide-induced Type 2 diabetes. J.Clin. Biochem.Nutr. 2009, 45(1): 29-36
- Hossein-nezhad, A., et al. Association of VDR gene polymorphism with insulin resistance in diabetic patients. Iranian Journal of Diabetes and Lipid Disorders. 2009, 143-150
- Komolafe, O.A., et al. Streptozotocin-induced diabetes alters the serum lipid profiles of adult Wistar rats. The internet Journal of Cardiovascular Research 2009, 7(1) doi: 10.5580/2251
- Lim, W,Y.A., et al. Lipoprotein lipase expression, serum lipid and tissue lipid deposition in orally administered glycyrrhizic acid-treated rats. Lipids in Health and Disease, 2009, 8: 31
- Perše, M., et al. Effect of high-fat mixed-lipid diet and exercise on the antioxidant system in skeletal and cardiac muscles of rats with colon carcinoma. Pharmacol. Rep. 2009, 61(5): 909-916
- Rhodes, P., et al. Adult-onset obesity reveals prenatal programming of glucose-insulin sensitivity in male sheep nutrient restricted during late gestation. PloS ONE 2009, 4(10): e7393
- Velasco-Martínez, R.M., et al. Obesity and insulin resistance among adolescents from Chiapas. Nutr. Hosp. 2009, 24(2)
- Eu, C.H.A., et al. Glycyrrhizic acid improved lipoprotein lipase expression, insulin sensitivity, serum lipid and lipid deposition in high-fat diet-induced obese rats. Lipids and Health Disease. 2010, 9: 81
- Mahadik, S.R. et al. Role of adipocytokines in insulin resistance: Studies from Urban Western Indian Population. Int. J. Diabetes & Metab. 2010, 18(9): 35-42
- Wonnacott, K.E. et al. Dietary omega-3 and-6 polyunsaturated fatty acids affect the composition and development of sheep granulose cells, oocytes and embryos. Reproduction. 2010, 139(1): 57-69
- Kojic, Z., et al. Effect of captopril on serum lipid levels and cardiac mitochondrial oxygen consumption in experimentally-induced hypercholesterolemia in rabbits. Physiol. Res. 2011, 60(1): S177-S184
- Srinivasa, G., et al. Comparison between serum insulin levels and its resistance with biochemical, clinical and anthropometric parameters in South Indian children and adolescents. Ind. J. Biochem. 2011, 26(1): 22-27
- Yahaya, N. et al. Type 2 diabetes with good glycemic control have improved insulin response and lower non-esterified fatty acid level after a meal challenge. Journal of Diabetes Mellitus 2012, 2(1): 1-7
Related Products
LDL Cholesterol
Reagent | LDL Cholesterol
Key Benefits
Exceptional correlation with standard methods
A correlation coefficient of r=0.99 was found when measured against the Ultracentrifugation method
Excellent stability
Stable to expiry when stored at +2 to +8°C
Other Features
- Direct Clearance Method
- Liquid ready-to-use reagents
- Correlation coefficient of r=0.99 with Ultracentrifugation method
- Stable to expiry when stored at +2 to +8°C
| Cat No | Size | ||||
|---|---|---|---|---|---|
| CH2656 | R1 6 x 78ml (L) R2 3 x 52ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| CH3841 | R1 3 x 51ml (L) R2 3 x 20ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| CH8032 | R1 4 x 19.2ml (L) R2 4 x 10.1ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| (L) Indicates liquid option | |||||
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is LDL Cholesterol assay used for?
Low Density Lipoproteins (LDL) are synthesised in the liver by the action of various Lipolytic enzymes on triglyceride rich Very Low Density Lipoproteins (VLDLs). Specific LDL receptors exist to facilitate the elimination of LDL from plasma by liver parenchymal cells. It has been shown that most of the cholesterol stored in atherosclerotic plaques originates from LDL. For this reason the LDL-Cholesterol concentration is considered to be the most important clinical predictor, of all single parameters, with respect to coronary atherosclerosis.
Accurate measurement of LDL-Cholesterol is of vital importance in therapies which focus on lipid reduction to prevent atherosclerosis or reduce its progress and to avoid plaque rupture.
It is recommended a patient get tested when aged 40; as part of a routine CV health check; if they are already thought to be at risk of CVD for another reason; or to monitor their response to treatments which lower LDL Cholesterol.
- Moloney, F., et al. Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus 1,2,3. Am. J. Clin. Nutr. 2004, 80(4): 887-895
- Nowak, M., et al. Changes in lipid metabolism in women with age-related macular degeneration. Clin. Exp. Med., 2005, 4(4): 183-187
- Chen, C-W and Cheng, H-H. A rice bran oil diet increases LDL-receptor and HMG-CoA reductase mRNA expressions and insulin sensitivity in rats with streptozotocin/nicotinamide-induced type 2 diabetes. J. Nutr. 2006, 136: 1472-1476
- Moreira Lima, L., et al. Níveis Plasmàticos Elevados de Lipoproteína(a) Correlacionados com a Gravidade da Doenca Arterial Coronariana em Pacientes Submetidos à Angiografia (Increased Serum Levels of Lipoprotein(a) Correlated with the Severity of Coronary Artery Disease in Patients Submitted to Angiography. Arquivos Brasileiros de Cardiologia. 2006, 87(3): 260-266
- Chou T-W., et al. A Rice bran oil diet improves lipid abnormalities and suppress hyperinsulinemic responses in rats with streptozotocin/nicotinamide-induced Type 2 diabetes. J.Clin. Biochem.Nutr. 2009, 45(1): 29-36
- Rhodes, P., et al. Adult-onset obesity reveals prenatal programming of glucose-insulin sensitivity in male sheep nutrient restricted during late gestation. PloS ONE 2009, 4(10): e7393
- Wonnacott, K.E. et al. Dietary omega-3 and-6 polyunsaturated fatty acids affect the composition and development of sheep granulose cells, oocytes and embryos. Reproduction. 2010, 139(1): 57-69
- Ganguli, D., et al. Association between inflammatory markers and cardiovascular risk factors in women from Kolkata, W.B, India. Arq. Bras. Cardiol. 2011, 96(1): Epub
- Srinivasa, G., et al. Comparison between serum insulin levels and its resistance with biochemical, clinical and anthropometric parameters in South Indian children and adolescents. Ind. J. Biochem. 2011, 26(1): 22-27
- Yahaya, N. et al. Type 2 diabetes with good glycemic control have improved insulin response and lower non-esterified fatty acid level after a meal challenge. Journal of Diabetes Mellitus 2012, 2(1): 1-7
High Sensitivity CRP
Reagent | High Sensitivity CRP
Key Benefits of the Randox High Sensitivity CRP
Limited Interference
From Conjugate and Free Bilirubin, Haemoglobin, Intralipid and Triglycerides
Wide measuring range
High Sensitivity CRP assay has a wide measuring range of 0.270 – 10 mg/l which will comfortably detect levels outside of the healthy range
Excellent stability
Stable to expiry when stored at 2-8⁰C
Randox High Sensitivity CRP (Latex Enhanced Immunoturbidimetric)
- Latex Enhanced Immunoturbidimetric method
- Liquid ready-to-use reagents
- Stable to expiry when stored at 2-8⁰C
- Measuring range 0.270-10 mg/l
Ordering information
| Cat No | Size | ||||
|---|---|---|---|---|---|
| CP3885 | R1 2 x 11ml(L) R2 2 x 11ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| (L) Indicates liquid option | |||||
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is High Sensitivity CRP assay used for?
C-reactive protein is present in serum of normal individuals at levels between 0-5mg/l. Research has indicated that CRP levels, which are within the normal range, can be used in a variety of different population subgroups for the assessment of cardiovascular risk for developing a fatal myocardial infarction. CRP levels within the normal range have been associated with coronary heart disease mortality in high-risk individuals. Elevated serum cholesterol levels, elevated diastolic blood pressure and cigarette smoking indicate high-risk.
A complete clinical history is required for accurate interpretation of CRP levels. CRP levels within the normal range may be affected by a number of different factors and should always be compared to previous values.
Cardiology Panel
For more information or to view more reagents within the cardiology panel, please click here
HDL Cholesterol
Reagent | HDL Cholesterol
Key Benefits
There are several methods available for measurement of HDL Cholesterol
Including Direct Clearance and Phosphotungstic Acid
Exceptional correlation with standard methods
A correlation coefficient of r=0.99 for the Precipitation and Ultracentrifugation methods, was verified against the CDC reference method
Excellent stability
Stable to expiry date when stored at +2 to +8ºC
HDL Cholesterol-Direct Clearance Method
- Direct Clearance Method
- Liquid ready-to-use reagents
- Stable to expiry when stored at 2-8°C
| Cat No | Size | ||||
|---|---|---|---|---|---|
| CH1383 | R1 3 x 2.5L (L) R2 1 x 2.5L | Enquire | Kit Insert Request | MSDS | Buy Online |
| CH2655 | R1 6 x 78ml (L) R2 3 x 52ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| CH3811 | R1 3 x 51ml (L) R2 3 x 20ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| CH8033 | R1 4 x 38.2ml (L) R2 4 x 18.2ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| CH8311 | R1 4 x 20ml (L) R2 4 x 9ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| (L) Indicates liquid option |
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
Randox HDL Cholesterol Precipitant-Phosphotungstic Acid
- AMP method
- Liquid and lyophilised reagents available
- Stable to expiry when stored at +15 to +25°C
- Wide measuring range of 0.071-23.7 mmol/l
| Cat No | Size | ||||
|---|---|---|---|---|---|
| CH203 * | 4 x 80ml (L) | Enquire | Kit Insert Request | MSDS | Buy Online |
| * CH203 is a precipitant product which can be used alongside the CHOD PAP assays (L) Indicates liquid option |
|||||
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is the HDL Cholesterol assay used for?
High-density lipoproteins (HDL) are one of the major classes of plasma lipoproteins. They are composed of a number of heterogeneous particles, including cholesterol and vary with respect to size and content of lipid and Apolipoprotein. HDL serves to remove cholesterol from the peripheral cells to the liver, where the cholesterol is converted to bile acids and excreted into the intestine.
Accurate measurement of HDL-C is of vital importance when assessing patient risk from CHD. Direct measurement gives improved accuracy and reproducibility when compared to precipitation methods.
HDL is usually requested with other tests, either with cholesterol or as part of a lipid profile, including LDL and triglycerides. The combination of total cholesterol and HDL is very useful for screening for the risk of heart disease.
Patients at risk include:
- Smokers
- Men over 45 years and women over 55 years
- Those with Hypertension (blood pressure 140/90 or higher or if taking medications for high blood pressure)
- Wallace, J.M.W., et al. Boron supplementation and activated factor VII in healthy men. EJCN 2002, 56(11): 1102-1107
- Joshi, S., et al. Fish oil supplementation of rats during pregnancy reduces adult disease in their offspring. J. Nutr., 2003, 133: 3170-3174
- Ghorbanihaghjo, A., et al. Effect of nandrolone decanoate on serum lipoprotein (a) and its isoforms in hemodialysis patients. Lipids Health Dis. 2004, 3: 16
- Saeed, B.O., et al. Comparison of three homogeneous methods for measuring high-density lipoprotein cholesterol with a precipitation method in diabetic and non-diabetic subjects. Br. J. Biomed. Sci., 2004, 61(4): 194-199
- Nowak, M., et al. Changes in lipid metabolism in women with age-related macular degeneration. Clin. Exp. Med., 2005, 4(4): 183-187
- Moreira Lima, L., et al. Níveis Plasmàticos Elevados de Lipoproteína(a) Correlacionados com a Gravidade da Doenca Arterial Coronariana em Pacientes Submetidos à Angiografia (Increased Serum Levels of Lipoprotein(a) Correlated with the Severity of Coronary Artery Disease in Patients Submitted to Angiography. Arquivos Brasileiros de Cardiologia. 2006, 87(3): 260-266
- Mineo, D., et al. Effects of lung volume reduction surgery for emphysema on glycolipidic hormones. Chest. 2008, 134(1): 30-37
- Bajaj, S., et al. A case-control study on insulin resistance, metabolic co-variates and prediction score in non-alcoholic fatty liver disease. Indian J. Med. Res. 2009, 129: 285-292
- Hossein-nezhad, A., et al. Association of VDR gene polymorphism with insulin resistance in diabetic patients. Iranian Journal of Diabetes and Lipid Disorders. 2009, 143-150
- Komolafe, O.A., et al. Streptozotocin-induced diabetes alters the serum lipid profiles of adult Wistar rats. The internet Journal of Cardiovascular Research 2009, 7(1) doi: 10.5580/2251
- Lim, W,Y.A., et al. Lipoprotein lipase expression, serum lipid and tissue lipid deposition in orally administered glycyrrhizic acid-treated rats. Lipids in Health and Disease, 2009, 8: 31
- Rhodes, P., et al. Adult-onset obesity reveals prenatal programming of glucose-insulin sensitivity in male sheep nutrient restricted during late gestation. PloS ONE 2009, 4(10): e7393
- Velasco-Martínez, R.M., et al. Obesity and insulin resistance among adolescents from Chiapas. Nutr. Hosp. 2009, 24(2)
- Eu, C.H.A., et al. Glycyrrhizic acid improved lipoprotein lipase expression, insulin sensitivity, serum lipid and lipid deposition in high-fat diet-induced obese rats. Lipids and Health Disease. 2010, 9: 81
- Mahadik, S.R. et al. Role of adipocytokines in insulin resistance: Studies from Urban Western Indian Population. Int. J. Diabetes & Metab. 2010, 18(9): 35-42
- Wonnacott, K.E. et al. Dietary omega-3 and-6 polyunsaturated fatty acids affect the composition and development of sheep granulose cells, oocytes and embryos. Reproduction. 2010, 139(1): 57-69
- Ganguli, D., et al. Association between inflammatory markers and cardiovascular risk factors in women from Kolkata, W.B, India. Arq. Bras. Cardiol. 2011, 96(1): Epub
- Kojic, Z., et al. Effect of captopril on serum lipid levels and cardiac mitochondrial oxygen consumption in experimentally-induced hypercholesterolemia in rabbits. Physiol. Res. 2011, 60(1): S177-S184
- Srinivasa, G., et al. Comparison between serum insulin levels and its resistance with biochemical, clinical and anthropometric parameters in South Indian children and adolescents. Ind. J. Biochem. 2011, 26(1): 22-27
- Hossein-nezhad, A. et al. Circulating omentin-1 in obesity and metabolic syndrome status compared to control subjects. Endocrinol. Metabol. Syndrome 2012: S1:008 doi:10.4172/2161-1017.S1-008
- Yahaya, N. et al. Type 2 diabetes with good glycemic control have improved insulin response and lower non-esterified fatty acid level after a meal challenge. Journal of Diabetes Mellitus 2012, 2(1): 1-7
Apolipoprotein B
Reagent | Apolipoprotein B (Immunoturbidimetric)
Key Benefits
Excellent stability
The Randox Apolipoprotein B (Immunoturbidimetric) is stable to expiry when stored at 2-8°C
Liquid ready-to-use reagents
Apolipoprotein B reagent comes in a liquid format which is more convenient, and can also help reduce the risk of errors occurring
Applications available
Applications available detailing instrument-specific settings for a variety of clinical chemistry analysers.
Ordering information
| Cat No | Size | ||||
|---|---|---|---|---|---|
| LP2117 | R1 4 x 50ml (L) (C) R2 4 x 9ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| LP3839 | R1 4 x 20ml (L) R2 4 x 6ml | Enquire | Kit Insert Request | MSDS | Buy Online |
| LP8008 | R1 2 x 10ml (L) R2 2 x 4ml | Enquire | Kit Insert Request | MSDS | Buy Online |
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
What is Apolipoprotein B assay used for?
The B Apolipoproteins are the main form of protein found in Low Density Lipoproteins (LDL). Two forms of APO B are found in humans. APO B is the main cholesterol carrying protein in the blood and is the ligand concerned with the uptake of cholesterol into cells by the LDL-receptor pathway. APO B shows atherogenic signs and is thus useful for the evaluation of coronary risk.
The test is undertaken:
- When the patient has a personal or family history of heart disease and/or high concentrations of lipids in the blood
- To determine the patient’s risk of developing CVD
- To help monitor treatment for hyperlipidaemia
- To help diagnose APO B deficiency
Apolipoprotein B Related Products
Apolipoprotein C-III (Apo C-III) Assay
Reagent | Apolipoprotein C-III (Apo C-III)
An Independent Risk Factor for CVD
Benefits of the Randox Apo C-lll Assay
Immunoturbidimetric method
The immunoturbidimetric method limits interference from Bilirubin, Haemoglobin, Intralipid® and Triglycerides, producing more accurate results.
Exceptional correlation
A correlation coefficient of r=1.00 was displayed when the Randox apo C-III assay was compared to commercially available methods.
Excellent measuring range
The Randox apo C-III assay has a measuring range of 2.06 – 21.7mg/dl for the comfortable detection of clinically important results.
Liquid ready-to-use
The Randox apo C-III assay is available in a liquid ready-to-use format for convenience and ease-of-use.
Dedicated calibrator and controls available
Randox offer dedicated apolipoprotein calibrator and controls for a complete testing package.
Applications available
Applications available detailing instrument-specific settings for the convenient use of the Randox apo C-III assay on a variety of clinical chemistry analysers.
Ordering Information
| Cat No | Size | ||||
|---|---|---|---|---|---|
| LP3865 | R1 2 x 11ml (L) R2 2 x 5ml | Enquire | Kit Insert Request | MSDS | Buy Online |
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
Clinical Significance
Not only is apo C-III a key regulator in the metabolism of triglycerides, but it is also an independent risk factor for CVD. Not only does apo C-III contribute to CVD through the regulation of triglycerides but also through its direct atherogenic effects, promoting atherosclerosis (fig 1) 1.
Fig. 1. Pleiotropic effects of apo C-III 1
Physiological Significance
Apo C-III is composed of 79 amino acids and has a molecular weight of 8.8kDa. Apo C-III promotes hypertriglyceridemia via several mechanisms. Firstly, like apo C-II, apo C-III also inhibits the activity of LPL, distributing lipid lipolysis. Apo C-III hinders the binding of apolipoprotein B and apolipoprotein E to the hepatic receptors resulting in the delayed catabolism of triglyceride – rich lipoproteins (TRLs). Finally, apo C-III prefers the production and secretion of very low-density lipoproteins (VLDL) in the liver 1.
Useful links
Reagents Home
Apolipoprotein Control
Apolipoprotein Calibrator
Extraction | Viral RNA Extraction Kit
Extraction | Reagent Kit
–
Viral RNA Extraction Kit
Designed to enable Automated Purification
- Extracts viral total nucleic acid (RNA) from nasal/throat swabs following brief lysis steps
- 200µl of sample from the nasal/throat swab required for analysis
- Universal kit which can be used for the efficient and automated purification of nucleic acid material
- Kit includes Lysis buffer, Proteinase K and Elution buffer material suitable for the extraction
- Yields highly concentrated nucleic acids that are ready to use in downstream applications such as qualitative or quantitative PCR
- Automated nucleic acid extraction platform available from Randox
The Randox Viral RNA Purification kit is designed for the optimal automated extraction of total nucleic acid (RNA) from nasal/throat samples.
Viral nucleic acid extraction is a critical step in infectious disease testing. Nucleic acid-based detection of viral pathogens requires the extraction of RNA allowing simultaneous detection of any viral infection.
Randox also offer a range of COVID-19 testing solutions including Molecular and Point of Care platforms along with RT-qPCR assays, Quality Controls and EQA schemes.
Want to know more?
Contact us or visit our COVID-19 Monitoring & Management page
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Viral Respiratory Infection Array
SARS-CoV-2 Rapid Test
Vivalytic
Vivalytic Test Menu
Superoxide Dismutase (Ransod)
Superoxide Dismutase (Ransod)
Benefits of the Randox Ransod Assay
Excellent correlation
A correlation coefficient of r=0.965 was displayed when the Randox Ransod assay was compared against commercially available methods.
Excellent precision
The Randox Ransod assay displayed a within run precision of <4.65% CV.
Excellent measuring range
The Randox Ransod assay has a measuring range of 0.00 – 5.50 U/ml for the comfortable detection of clinically important results.
Standard included in kit
The standard is supplied with the Ransod kit, simplifying the ordering process.
Dedicated Ransod control available
A dedicated Ransod control is available offering a complete testing package.
Applications available
Applications available detailing instrument-specific settings for the convenient use of the Randox Ransod assay on a variety of clinical chemistry analysers.
Ordering information
Instrument Specific Applications (ISA’s) are available for a wide range of biochemistry analysers. Contact us to enquire about your specific analyser.
| Cat No | Size | ||||
|---|---|---|---|---|---|
| SD125 | 5 x 20ml (S) | Enquire | Kit Insert Request | MSDS | Buy Online |
| (S) Indicates standard included in kit | |||||
Superoxide dismutase (SOD) are a group of metalloenzymes, the first line of defence against reactive oxygen species (ROS)-medicated injury. SOD is responsible for catalysing the dismutation of the superoxide anion free radical (O2–) into molecular oxygen and hydrogen peroxide (H2O2). The aim of this process is to reduce the levels of O2– as it damages cells at excessive concentrations 1.
SOD is the most important antioxidant defence against oxidative stress. SOD is a severe anti-inflammatory agent and can prevent precancerous cell changes. Reduced SOD levels have been observed in older generations as SOD levels drop as the body ages and so are more prone to oxidative related diseases. Reduced SOD activity has been identified as having a strong correlation with Alzheimer’s Disease. The overexpression of SOD-2 reduces hippocampal superoxide, preventing memory defects 1. Moreover, SOD has been identified as a potential diagnostic and prognostic marker in patients with gastric cancer 2. SOD has also been linked to other health conditions, including: rheumatoid arthritis, RBC-related disorders, Crohn’s Disease, cystic fibrosis, malignant breast cancer and neuronal apoptosis 1, 3.
Fig. 1. Pathological effects associated with SOD gene mutation or SOD deficiency 4
Related Products
Ransod Control
Antioxidants Panel
Reagents Home
Reagents Resource Hub
RX modena and Randox Reagents used in COVID-19 hospital in India
RX modena and Randox Reagents used in COVID-19 hospital in India
Randox Laboratories has installed an RX modena into a COVID-19 hospital in India; the Netaji Subhash Chandra Bose Medical College in Madhya Pradesh state.
The installation, which marks the first RX modena to be used in an Indian Government Medical College, replaces existing instrumentation in the Medical College laboratory, an initiative which was driven by College Dean Dr. Pradeep Kumar Kasar and Head of Department Dr. Ashok Kumar Sahu.
The RX modena will cater for an additional 38 samples compared to the previous instrumentation, and is running a range of biochemistry tests that play a pivotal role in COVID-19 patient management, including C-Reactive Protein (CRP), Ferritin, and Lactate Dehydrogenase (LDH).
Dr. Ashok Kumar Sahu, Head of Biochemistry at Netaji Subhash Chandra Bose Medical College, commented;
“We are very pleased with the performance of the RX modena, and in particular with its wide menu of tests that can be utilized for COVID-19 patient management. Its high throughput and versatility have been a great support for the clinicians working in our COVID-19 hospital, in determining risk stratification, disease progression, and response to treatment.”
The RX modena is a high volume, floor standing, fully automated clinical chemistry analyser with a world leading test menu which covers specific proteins, lipids, therapeutic drugs, antioxidants, diabetes and veterinary testing. The versatile analyser offers advanced methodologies with excellent correlation to the gold standard, and excellent reagent CV ranges.
Shail Dholabhai, Randox India Sales Manager, commented;
“We are delighted that the team at Netaji Subhash Chandra Bose Medical College have chosen the RX modena to fulfil the testing requirements of this COVID-19 hospital. Offering an unrivalled test menu of routine and specialized chemistries, the RX modena provides laboratories with the superior precision, reliability and accuracy that the Randox RX series is renowned for.
“Capable of performing a total of 1200 tests per hour including ISE, the RX modena presents a new class of efficiency which will result in faster and more accurate diagnoses, and ultimately, lead to better patient outcomes.”
Benefits of the RX modena
- Capable of performing 800 photometric and a total of 1200 tests per hour including ISE.
- World-leading extensive test menu covering routine chemistries, specific proteins, lipids, antioxidants, cardiac, diabetes and veterinary testing, offering cost savings through consolidation of routine and novel tests on a single platform.
- Economic platform with low water consumption of less than 20 litres per hour saving on consumable costs. The RX modena also requires less than 5 minutes minimal maintenance.
- Interactive touch-screen technology with integrated barcode readers for reagent and sample identification. Increased functionality with 13 wavelengths generated via diffraction grating (340-800nm) ensuring a multitude of chemistries are possible on one system.
- Easy-to-use advanced Microsoft 10 software with a built-in Inventory Management System calculating the number of tests remaining, providing alerts of shortages and expired reagents and calibrators. The RX modena also features automatic test re-run function and sample dilution.
- Dedicated reagent and sample pipettes to minimise the risk of errors and contamination. The RX modena also features a continuous loading hatch to allow for samples to be analysed quickly and easily during a run.
- Advanced QC capabilities with daily, monthly and batch QC with data archiving, Levey-Jennings charts and automatic QC and calibration. There are also 7 different calibration options available.
For further information about the RX modena click here.
For information about laboratory tools for COVID-19 patient management please click here.
For other enquiries please contact marketing@randox.com
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